Grape skin (Vitis Vinifera) is rich in polyphenols, especially resveratrol, which is renowned for its ability to support heart health, reduce inflammation, and fight oxidative stress. Resveratrol has been studied for its potential to extend longevity and improve cardiovascular function. Grape skin also contains other antioxidants that support overall health and protect against cellular damage.

Key Highlights Grape Skin

• Beneficial for age-related memory decline
• Helps to fight the signs of ageing
• A powerful antioxidant which can help with signs of ageing including skin and disease
• Can supports heart health

Biochemistry Timeline

Grape skin extract supplementation may take about four weeks for noticeable benefits, such as improved cardiovascular health and antioxidant support. However, some internal effects can be felt within 24 hours due to its non-essential nature, meaning any intake can prompt a quick physiological response.

What is Grape Skin Extract?

You may have heard that the odd glass of wine can be good for you, and here’s why. Since ancient Greece, grapes have been valued for their therapeutic properties. More recently, sap from grape branches has been used to treat skin issues and scrapes.

Polyphenols found in grape skin extract are among the most powerful antioxidants. They protect heart and brain tissues, improve digestion, fight diabetes, and prevent cardiovascular and neurodegenerative diseases. Additionally, these polyphenols can enhance skin health, provide anti-inflammatory benefits, and support overall immune function, making them a potent ally in maintaining optimal health.

The Amazing Benefits of Grape Skin Extract:

High in Antioxidants

We talk a lot about antioxidants because they are crucial for our health, naturally helping us combat harmful free radicals. Due to its high antioxidant content, grape skin extract can help prevent diseases and protect against free radical damage.

Prevention of Chronic Diseases

Resveratrol, a powerful compound found in grapes, plays a beneficial role in preventing and slowing the progression of chronic diseases related to inflammation. These include diabetes, obesity, cardiovascular diseases, neurodegenerative disorders, and various cancers. Additionally, resveratrol supports overall cellular health, making it a valuable component of a healthy diet.

Anti-ageing

Polyphenols like Resveratrol in grape skin have the ability to neutralize free radicals that can damage skin. Resveratrol is effective for anti-ageing due to its dual properties that can neutralise free radicals and also increase antioxidant capacity. These compounds help protect the skin from free radical damage, reducing signs of ageing such as wrinkles and fine lines. Additionally, they improve skin elasticity and hydration, giving the skin a more youthful and radiant appearance.

Anti-inflammatory

Furthermore, grape skin extract has anti-inflammatory properties, which can help soothe irritated skin and reduce redness, and offer hydrating effects. Resveratrol has been found to help protect against UV damage and can even reduce pigmentation caused by the sun. It also promotes collagen production, which is essential for maintaining skin firmness and structure. Regular use of products containing grape skin extract can result in smoother, healthier, and more resilient skin.

Memory and Mood Benefits

Owing to their polyphenol-rich properties, especially resveratrol and their free radical scavenging actions, grape skin extract intake exhibits beneficial properties in protecting against cognitive decline.

Studies have reported that resveratrol provides apparent benefits for age-related learning, memory, and mood functions. Resveratrol may even help people afflicted with severe neurodegenerative conditions such as Alzheimer's disease. By reducing inflammation and oxidative stress in the brain, resveratrol supports overall cognitive health and could potentially slow the progression of neurodegenerative disorders, making it a valuable addition to a neuroprotective diet.

Summary

Grape skin extract (Vitis Vinifera) is rich in polyphenols, particularly resveratrol, known for supporting heart health, reducing inflammation, and fighting oxidative stress. It offers benefits for age-related memory decline and skin aging. While noticeable effects on cardiovascular health may take about four weeks, some internal benefits can be felt within 24 hours. This extract enhances overall health, protects against cellular damage, and supports immune function. Its antioxidants improve skin elasticity, hydration, and collagen production, while also providing neuroprotective benefits against cognitive decline, making it a valuable addition to a health regimen.

FAQs

How much Grape Skin Extract should I take daily? Typical dosages range from 100 to 300 mg of standardized extract per day. It’s best to follow product guidelines or consult a healthcare professional for personalized advice.

Are there any side effects associated with Grape Skin Extract? Grape Skin Extract is generally safe for most people. However, some may experience mild gastrointestinal discomfort or allergic reactions. Always consult a healthcare provider if you have concerns.

How long does it take to see benefits from Grape Skin Extract? While some internal benefits may be felt within 24 hours, noticeable improvements, particularly in cardiovascular health and antioxidant support, may take about four weeks of consistent supplementation.

Research:

1. Malaguarnera L. (2019). Influence of Resveratrol on the Immune Response. Nutrients, 11(5), 946.
2. Jariyapamornkoon, N., Yibchok-anun, S. & Adisakwattana, S. (2013) Inhibition of advanced glycation end products by red grape skin extract and its antioxidant activity. BMC Complementary Alternative Medecine, 13, 171.
3. Farris, P., Yatskayer, M., Chen, N., Krol, Y., & Oresajo, C. (2014). Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin. Journal of drugs in dermatology : JDD, 13(12), 1467–1472.
4. Boo Y. C. (2019). Human Skin Lightening Efficacy of Resveratrol and Its Analogs: From in Vitro Studies to Cosmetic Applications. Antioxidants (Basel, Switzerland), 8(9), 332.
5. Buonocore, D., Lazzeretti, A., Tocabens, P., Nobile, V., Cestone, E., Santin, G., Bottone, M. G., & Marzatico, F. (2012). Resveratrol-procyanidin blend: nutraceutical and antiaging efficacy evaluated in a placebocontrolled, double-blind study. Clinical, cosmetic and investigational dermatology, 5, 159–165.
6. Singh, C. K., Liu, X., & Ahmad, N. (2015). Resveratrol, in its natural combination in whole grape, for health promotion and disease management. Annals of the New York Academy of Sciences, 1348(1), 150–160.
7. Cicero, A. F. G., Ruscica, M., & Banach, M. (2019). Resveratrol and cognitive decline: a clinician perspective. Archives of medical science : AMS, 15(4), 936–943.
8. Kodali, M., Parihar, V. (2015) Hattiangady, B. et al. Resveratrol Prevents Age-Related Memory and Mood Dysfunction with Increased Hippocampal Neurogenesis and Microvasculature and Reduced Glial Activation. Scientific Reports, 5, 8075.
9. Fan, M., Kim, S. A., Choi, Y. J., Tang, Y., Yang, H. P., & Kim, E. K. (2023). Anthocyanin oligomer (grape skin extract) administration improves dry eye disease: A randomised, double-blind, placebo-controlled study. Clinical & experimental ophthalmology, 51(2), 122–130.
10. Asbaghi, O., Nazarian, B., Reiner, Ž., Amirani, E., Kolahdooz, F., Chamani, M., & Asemi, Z. (2020). The effects of grape seed extract on glycemic control, serum lipoproteins, inflammation, and body weight: A systematic review and meta-analysis of randomized controlled trials. Phytotherapy research : PTR, 34(2), 239–253.